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<div class="moz-cite-prefix">Hi Piers,<br>
<br>
In two studies we found a similar pattern (larger left ear N100
responses). This seems to be due to a relatively stronger right
hemisphere involvement, which causes an asymmetry in the degree of
contralateral responses between left and right ear. <br>
<br>
Hine J, Thornton R, Davis A, Debener S. (2008). Does long-term
unilateral deafness change auditory evoked potential asymmetries?<br>
Clin Neurophysiol. 119(3):576-86.<br>
<br>
Hine J, Debener S.(2007). Late auditory evoked potentials
asymmetry revisited.<br>
Clin Neurophysiol. 118(6):1274-85.<br>
<br>
A similar result has been reported for MEG as well.<br>
<br>
Best,<br>
Stefan<br>
<br>
<br>
<br>
Am 7/12/12 12:47 PM, schrieb Piers Dawes:<br>
</div>
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<p class="MsoNormal">Dear list<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">We have obtained an odd asymmetric auditory
ERP. Does anyone have an explanation? Any suggestions would be
welcome.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">We recorded ERPs to pure tone beeps of 500
and 3000 Hz at 3 intensity levels. Tones were randomised and
played separately to left and right ears, with responses
recorded at Cz with a nose tip reference using a Neuroscan
system. Insert headphones were calibrated before testing and
re-checked after; left and right headphones provide identical
levels of output. Participants were 58 older people (mean age
70 years) with age-related hearing loss (Mean HL of 45 dB at
2kHz). Selection criteria included symmetrical hearing (not
greater than 15dB difference at any frequency), and overall
mean HL is symmetrical.
<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Grand mean ERPs are higher in amplitude for
tones played to left ear compared to right ear (by about ~1uV
for N1 and ~.5uV for P2), and this is a consistent pattern
among participants. Latencies are similar. I would have
thought amplitudes should also be very similar between left
and right ear. What is happening here?<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thanks for your help<o:p></o:p></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">Piers
Dawes PhD<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">Audiology
and Deafness Research Group<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">School
of Psychological Sciences<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">Ellen
Wilkinson Building<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">University
of Manchester<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">Manchester
M13 9PL<o:p></o:p></span></p>
<p class="MsoNormal"><span
style="font-size:10.0pt;font-family:"Arial","sans-serif";color:navy">Tel:
+44 (0)161 30 61758</span><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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<pre class="moz-signature" cols="72">--
Prof. Dr. Stefan Debener
Neuropsychology Lab
Department of Psychology
University of Oldenburg
D-26111 Oldenburg
Germany
Office: A7 0-038
Phone: +49-441-798-4271
Fax: +49-441-798-5522
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