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<p class="MsoNormal">Hello all,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I performed a wavelet analysis in EEGlab to get both ERSP and ITC measures for auditory oddball data from a clinical population and healthy controls. I am doing non-parametric permutation testing on the output to determine significantly
different regions in responses to target stimuli between healthy and clinical populations, and the same for between-group response to standard stimuli.
<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">In Plot Channel Measures <span style="font-family:Wingdings">
à</span> Stats, I selected the options to compute 1<sup>st</sup> and 2<sup>nd</sup> independent variable statistics, EEGlab permutation statistics, threshold p-value of 0.05 and an FDR correction (randomization: auto).<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I have a couple questions:<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoListParagraph" style="text-indent:-.25in;mso-list:l0 level1 lfo1"><![if !supportLists]><span style="mso-list:Ignore">1)<span style="font:7.0pt "Times New Roman"">
</span></span><![endif]>I performed my wavelet analysis on single trial data; is it common practice to also perform the permutation testing on the single trial data? When I try to select the “Use Single Trials” option I get a message that I will have to precompute
the channel measures again and save the single trials, so I am wondering if this is necessary.<o:p></o:p></p>
<p class="MsoListParagraph" style="text-indent:-.25in;mso-list:l0 level1 lfo1"><![if !supportLists]><span style="mso-list:Ignore">2)<span style="font:7.0pt "Times New Roman"">
</span></span><![endif]>I have read studies that have done permutation testing on time-frequency data to determine significantly different regions between conditions within the same subjects. However, is it okay to do this permutation testing comparing the
data of a healthy population and a clinical population, given that they may have different noise characteristics? Anything I should consider in this case?<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thank you very much for any advice.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Nancy<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><b><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black;background:white">Nancy Lundin</span></b><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black">Doctoral Student, Clinical Psychology & Neuroscience</span></b><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black">Indiana University Bloomington</span><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black">Department of Psychological & Brain Sciences</span><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black">1101 East 10th St.</span><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;font-family:"Times New Roman",serif;color:black">Bloomington, IN 47405</span><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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