<div dir="ltr">Dear Nancy,<div><br></div><div><p>> 1)<span style="font-stretch:normal;font-size:7pt;font-family:'Times New Roman'"> </span><u></u>I performed my wavelet analysis on single trial data; is it common practice to also perform the permutation testing on the single trial data? When I try to select the “Use Single Trials” option I get a message that I will have to precompute the channel measures again and save the single trials, so I am wondering if this is necessary.</p><p>In a common practice, we do NOT use single-trial variance from a single-subject data (separate from the argument whether it is a good practice or not...)</p><p>> 2)<span style="font-stretch:normal;font-size:7pt;font-family:'Times New Roman'"> </span>However, is it okay to do this permutation testing comparing the data of a healthy population and a clinical population, given that they may have different noise characteristics? Anything I should consider in this case?<br></p></div><div class="gmail_extra">It is okay.</div><div class="gmail_extra"><br></div><div class="gmail_extra">Makoto</div><div class="gmail_extra"><br></div><div class="gmail_extra"><br></div><div class="gmail_extra"><br><div class="gmail_quote">On Mon, Aug 15, 2016 at 3:34 PM, Lundin, Nancy B. <span dir="ltr"><<a href="mailto:nlundin@indiana.edu" target="_blank">nlundin@indiana.edu</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex">
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<p class="MsoNormal">Hello all,<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal">I performed a wavelet analysis in EEGlab to get both ERSP and ITC measures for auditory oddball data from a clinical population and healthy controls. I am doing non-parametric permutation testing on the output to determine significantly
different regions in responses to target stimuli between healthy and clinical populations, and the same for between-group response to standard stimuli.
<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal">In Plot Channel Measures <span style="font-family:Wingdings">
à</span> Stats, I selected the options to compute 1<sup>st</sup> and 2<sup>nd</sup> independent variable statistics, EEGlab permutation statistics, threshold p-value of 0.05 and an FDR correction (randomization: auto).<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal">I have a couple questions:<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p><u></u><span>1)<span style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:'Times New Roman'">
</span></span><u></u>I performed my wavelet analysis on single trial data; is it common practice to also perform the permutation testing on the single trial data? When I try to select the “Use Single Trials” option I get a message that I will have to precompute
the channel measures again and save the single trials, so I am wondering if this is necessary.<u></u><u></u></p>
<p><u></u><span>2)<span style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:'Times New Roman'">
</span></span><u></u>I have read studies that have done permutation testing on time-frequency data to determine significantly different regions between conditions within the same subjects. However, is it okay to do this permutation testing comparing the
data of a healthy population and a clinical population, given that they may have different noise characteristics? Anything I should consider in this case?<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal">Thank you very much for any advice.<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal">Nancy<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal"><b><span style="font-size:12pt;font-family:'Times New Roman',serif;color:black;background:white">Nancy Lundin</span></b><span style="font-size:12pt;font-family:'Times New Roman',serif"><u></u><u></u></span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:10pt;font-family:'Times New Roman',serif;color:black">Doctoral Student, Clinical Psychology & Neuroscience</span></b><span style="font-size:12pt;color:black"><u></u><u></u></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10pt;font-family:'Times New Roman',serif;color:black">Indiana University Bloomington</span><span style="font-size:12pt;color:black"><u></u><u></u></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10pt;font-family:'Times New Roman',serif;color:black">Department of Psychological & Brain Sciences</span><span style="font-size:12pt;color:black"><u></u><u></u></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10pt;font-family:'Times New Roman',serif;color:black">1101 East 10th St.</span><span style="font-size:12pt;color:black"><u></u><u></u></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10pt;font-family:'Times New Roman',serif;color:black">Bloomington, IN 47405</span><span style="font-size:12pt;color:black"><u></u><u></u></span></p>
<p class="MsoNormal"><u></u> <u></u></p>
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