[Eeglablist] Auditory steady-state response and ERP analysis pre-processing steps

Michael Boyle mrboyle at live.unc.edu
Tue Aug 18 11:54:18 PDT 2015


Dear EEGLABers,

I would like to know whether or not the particular pre-processing steps
listed are recommended for ERP analysis, time-frequency analysis (wavelet
amplitude spectrograms or DFT spectrograms, ITPC), and source localization
analysis.

In particular, I am uncertain about the ordering of steps such as
interpolating bad channels before or after re-referencing or ICA, or if
particular steps work for some analysis strategies but not others (e.g. if
a preprocessing step would work fine for time-frequency analysis but not be
appropriate for source localization). Any feedback is much appreciated!

0. Start with 128-channel EEG from EGI HydroCel Geodesic Sensor Net, with
flags indicating events and epochs around events predefined (-0.1s to 0.9s
around the events).
1. Keep all valid (even if lots of line noise) channels in dataset, only
remove channels which clearly have no physiological information.
2. Epoch the data, reject bad epochs by eye (significant movement or rare,
not-stereotyped artifacts)
3. Run ICA on epoched data.
4. Reject components related to blinks, stereotypical muscle activity, and
60 Hz noise, and EKG artifacts.
5. Reconstruct sensor-level signals from remaining ICA weights
6. Re-reference all cleaned EEG channels to the average reference
7. Interpolate (using spherical splines from neighboring electrodes) any
channels that were rejected in step 1.
8. Calculate ERPs, time-frequency analysis, source localization

Best and many thanks,
Michael
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