[Eeglablist] bispectral index (BIS) plug-in for EEGLAB
ijaganjac09 at gmail.com
Thu Dec 3 06:59:17 PST 2015
Excellent point. Please note that details of bispectral index (BIS)
algorithm are protected in patent. The Medtronic/Covidien 4-channel
BIS monitor is certified by the FDA.
Also, please note that Philips Healthcare Systems has certified BIS
monitor as well:
In my view, it is possible to compute BIS index values (0-100) in
EEGLAB (after artifact removal and ICA analysis), by combining power
spectrum and bispectrum and burst suppression.
Please see this scientific report of Brazilian team:
On 12/3/15, Satoshi Hagihira <hagihira at masui.med.osaka-u.ac.jp> wrote:
> Dear I. Jaganjac
> The algorithm of bispectral analysis for EEG has arleady been
> established. However, we cannot calculate BIS (Bispectral Index), because
> the manufacturer didn't make its calculating algorithm in public domain.
> Only three articles described how BIS was calculated, but none were in
> And all three articles contained errors.
> Furthermore, the developers of BIS argolithm had left the company. It
> is now immpossible to know the exact argolithm of calculating BIS.
> Bispectral Index is quite popular in anesthesia field. But it has many
> problems. BIS is calculated from three or four EEG derived sub-parameters
> combined with coefficients obtained by multi-variate analysis of an EEG
> database. It is not a "measured" value, but merely a "predicted" value.
> BIS includes some estimation error, and it sometimed not small.
> I personally think that we should not use BIS for pure scientific research,
> because it is quite difficult to evaluate its true meaning.
> best regards,
> by Satoshi Hagihira, MD, PhD
> Associate Professor,
> Department of Anesthesiology and Intensive Care Medicine,
> Osaka University Graduate School of Medicine,
> 2-2 Yamadaoka, Suita City, Osaka, 565-0871
> Tel. +81-6(6879)3133, Fax. +81-6(6879)3139
> hagihira at masui.med.osaka-u.ac.jp
More information about the eeglablist