[Eeglablist] Codes for cluster correction are needed

[Olivia Yang]

Hi Cyril，

Thank you very much for your kind reply with detailed explanations!

However, FDR correction is too conservative in my case. So, I’d like to use alternative correction methods that can take space information into consideration.

I thought it would be easy to finish cluster corrections for peak amplitude statistics in EEGLAB. But it looks like not.

Best wishes,
Olivia

------- Original Message -------
On Wednesday, July 20th, 2022 at PM 3:18, Dr Cyril, Pernet <wamcyril at gmail.com> wrote:


> Hi Olivia
>
> clustering requires some continuity over space and/or time - here you
> have a 30 (Subjects) × 4 (Conditions in my experiment) × 66 (Channels)
> matrix of peak values so could cluster over space but I would really not
> recommend doing that as these a 'peaks' so really different measurements
> at each channels - in your case I'd test whatever differences you are
> interested in and apply an FDR correction.
>
> more info from a good old EEGLAB lecture
> https://urldefense.com/v3/__https://figshare.com/articles/presentation/Statistical_analysis_of_EEG_data_Hierarchical_modelling_and_multiple_comparisons_correction/4233977__;!!Mih3wA!GBIn8vR710MhPHql1cYpKBehOg9lKFgiQIl50rFqAb1SkCmQlTiyEvCGOI4-C5_ZML04IHhFfgqIyRExOxBDFr2WESLJ$ 
> slides 2 and 3 gives you an idea why I'd not recommend your approach
> above and slides 24+ explains multiple comparison corrections and among
> those procedure, clustering.
>
> reference article
> https://urldefense.com/v3/__https://www.sciencedirect.com/science/article/pii/S0165027014002878__;!!Mih3wA!GBIn8vR710MhPHql1cYpKBehOg9lKFgiQIl50rFqAb1SkCmQlTiyEvCGOI4-C5_ZML04IHhFfgqIyRExOxBDFuz3yz3P$ 
>
> cyril
>
> > Dear EEGLAB geniuses,
> >
> > Do you know whether there are codes for performing cluster corrections?
> >
> > After I finished the preprocessing analysis in EEGLAB, I picked out peak values of N170 from average waveforms through custom Matlab codes. And a 30 (Subjects) × 4 (Conditions in my experiment) × 66 (Channels) matrix of peak values was generated. Afterwards, I conducted repeated measure ANOVA and got statistical values of each channel.
> >
> > Now I need to perform multiple comparison corrections (cluster correction) for the comparison of peak value difference among the four conditions. Are there codes or more effortless ways that can help me?
> >
> > Looking forward to your reply!
> >
> > Cheers!
> >
> > Best regards,
> >
> > Olivia
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>
> --
> Dr Cyril Pernet, PhD, OHBM fellow, SSI fellow
> Neurobiology Research Unit,
> Building 8057, Blegdamsvej 9
> Copenhagen University Hospital, Rigshospitalet
> DK-2100 Copenhagen, Denmark
>
> wamcyril at gmail.com
> https://urldefense.com/v3/__https://cpernet.github.io/__;!!Mih3wA!GBIn8vR710MhPHql1cYpKBehOg9lKFgiQIl50rFqAb1SkCmQlTiyEvCGOI4-C5_ZML04IHhFfgqIyRExOxBDFlXk4eZS$ 
> https://urldefense.com/v3/__https://orcid.org/0000-0003-4010-4632__;!!Mih3wA!GBIn8vR710MhPHql1cYpKBehOg9lKFgiQIl50rFqAb1SkCmQlTiyEvCGOI4-C5_ZML04IHhFfgqIyRExOxBDFle1Szv0$